Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14396307 | 0.89 | BCHE (0.51) | BCHEACHEATMCTSLCTSS | |
| SCHEMBL14396308 | 0.89 | BCHE (0.51) | BCHEACHEATMCTSLCTSS | |
| SCHEMBL4033719 | 0.84 | NPC1 (0.65) | ATMCTSLCTSSCTRB1NPC1 | |
| SCHEMBL13534727 | 0.84 | NPC1 (0.65) | ATMCTSLCTSSCTRB1NPC1 | |
| SCHEMBL5914431 | 0.83 | NPC1 (0.51) | BCHEACHENPC1RAB9A | |
| SCHEMBL5914427 | 0.83 | NPC1 (0.51) | BCHEACHENPC1RAB9A | |
| SCHEMBL5948117 | 0.83 | NPC1 (0.51) | BCHEACHENPC1RAB9A | |
| SCHEMBL4001568 | 0.83 | NPC1 (0.51) | BCHEACHENPC1RAB9A | |
| SCHEMBL2985968 | 0.82 | ALDH1A1 (0.52) | ATMCTSLCTSSCTRB1NPC1 | |
| SCHEMBL5263402 | 0.82 | SIGMAR1 (0.51) | ATMCTSLCTSSCTRB1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114827-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2007-10-11 | — | — | WO | disclosed |