Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292144 | 0.92 | LMNA (0.32) | LMNAHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14397234 | 0.89 | LMNA (0.33) | LMNAHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14397236 | 0.86 | HSD17B10 (0.34) | LMNAHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12292129 | 0.85 | HSD17B10 (0.43) | LMNAHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14397239 | 0.85 | ALDH1A1 (0.33) | LMNAHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14397235 | 0.84 | LMNA (0.31) | LMNAHSD17B10SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL14397237 | 0.83 | POLB (0.31) | LMNAHSD17B10POLB | |
| SCHEMBL14397238 | 0.82 | MAPT (0.35) | HSD17B10SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL12292148 | 0.80 | LMNA (0.34) | LMNAHSD17B10MEN1KMT2AMAPT | |
| SCHEMBL14535349 | 0.77 | KMT2A (0.35) | LMNAHSD17B10SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113119-A1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2007-10-11 | — | — | WO | disclosed |