Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 4/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292141 | 0.92 | MAPT (0.35) | MAPTUTS2RALDH1A1NPC1TP53 | |
| SCHEMBL14397239 | 0.89 | ALDH1A1 (0.33) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL14397235 | 0.86 | LMNA (0.31) | ALDH1A1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL14397234 | 0.84 | LMNA (0.33) | MAPTALDH1A1SMN1; SMN2HSD17B10KMT2A | |
| SCHEMBL14397233 | 0.82 | LMNA (0.32) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL12292150 | 0.81 | RAB9A (0.33) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL14397236 | 0.81 | HSD17B10 (0.34) | MAPTSMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL12292110 | 0.79 | LMNA (0.42) | MAPTUTS2RALDH1A1NPC1TP53 | |
| SCHEMBL11088984 | 0.78 | NR4A2 (0.40) | MAPTALDH1A1NPC1TP53RAB9A | |
| SCHEMBL12292151 | 0.75 | MAPT (0.33) | MAPTHPGDKMT2AMEN1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113119-A1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2007-10-11 | — | — | WO | disclosed |