Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292150 | 0.91 | RAB9A (0.33) | ALDH1A1SMN1; SMN2HSD17B10NPC1TP53 | |
| SCHEMBL14397238 | 0.89 | MAPT (0.35) | ALDH1A1SMN1; SMN2HSD17B10NPC1TP53 | |
| SCHEMBL14397235 | 0.89 | LMNA (0.31) | ALDH1A1SMN1; SMN2HSD17B10KMT2ALMNA | |
| SCHEMBL14397234 | 0.87 | LMNA (0.33) | ALDH1A1SMN1; SMN2HSD17B10KMT2AMEN1 | |
| SCHEMBL14397233 | 0.85 | LMNA (0.32) | ALDH1A1SMN1; SMN2HSD17B10NPC1TP53 | |
| SCHEMBL14397236 | 0.84 | HSD17B10 (0.34) | SMN1; SMN2HSD17B10KMT2AMEN1LMNA | |
| SCHEMBL14397237 | 0.81 | POLB (0.31) | HSD17B10LMNA | |
| SCHEMBL12292141 | 0.81 | MAPT (0.35) | ALDH1A1SMN1; SMN2HSD17B10NPC1TP53 | |
| SCHEMBL12292151 | 0.78 | MAPT (0.33) | HPGDKMT2AMEN1LMNAMAPT | |
| SCHEMBL12292148 | 0.78 | LMNA (0.34) | ALDH1A1HSD17B10KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113119-A1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2007-10-11 | — | — | WO | disclosed |