Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 2/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.59 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL28195209 | 0.98 | CA12 (0.61) | CA12CA2CA9EPHX1PLAAT5 | |
| SCHEMBL1953254 | 0.88 | L3MBTL1 (0.68) | EPHX1NPC1RAB9AALDH1A1TAAR1 | |
| Propylene Glycol SCHEMBL28725243 | 0.87 | KMT2A (0.54) | CA12CA2CA9EPHX1PLAAT5 | |
| Hydrochloric Acid SCHEMBL27759637 | 0.86 | L3MBTL1 (0.66) | EPHX1NPC1RAB9AALDH1A1TAAR1 | |
| SCHEMBL1955322 | 0.86 | TRPV1 (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1952776 | 0.85 | TRPV1 (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1955741 | 0.85 | TRPV1 (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1954419 | 0.85 | TRPV1 (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1955588 | 0.85 | TRPV1 (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1955492 | 0.85 | TRPV1 (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263329-B | Methods and compositions for weed control | 孟山都技术公司 | 2020-09-18 | — | — | CN | claimed |
| US-10609930-B2 | Methods and compositions for weed control | MONSANTO TECHNOLOGY LLC (US) | 2020-04-07 | — | — | US | claimed |
| US-10612019-B2 | Methods and compositions for weed control | MONSANTO TECHNOLOGY LLC (US) | 2020-04-07 | — | — | US | claimed |
| US-10568328-B2 | Methods and compositions for weed control | MONSANTO TECHNOLOGY LLC (US) | 2020-02-25 | — | — | US | claimed |
| EP-3604535-A2 | METHODS AND COMPOSITIONS FOR WEED CONTROL | Monsanto Technology LLC (US) | 2020-02-05 | — | — | EP | claimed |
| EP-3390355-A1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | Helsinn Healthcare S.A. (CH) | 2018-10-24 | — | — | EP | claimed |
| WO-2017162390-A1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2017-09-28 | — | — | WO | claimed |
| CN-106458868-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-105452462-A | Methods and compositions for weed control | MONSANTO TECHNOLOGY LLC | 2016-03-30 | — | — | CN | claimed |
| US-20160029644-A1 | Methods and Compositions for Weed Control | MONSATO TECHNOLOGY LLC (US) | 2016-02-04 | — | — | US | claimed |
| US-20050234081-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | SUBASINGHE NALIN | 2005-10-20 | — | — | US | claimed |
| EP-1549632-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2005-07-06 | — | — | EP | claimed |
| US-20040009995-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2004-01-15 | — | — | US | claimed |
| WO-2003099805-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-12-04 | — | — | WO | claimed |
| CN-1369496-A | Use of compound with structure similar to L-phenylalanine as medicine to treat skin diseases | LU XIAODE (CN) | 2002-09-18 | — | — | CN | claimed |
| EP-0687251-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-12-20 | — | — | EP | claimed |
| US-5401766-A | Hypotensive agents with vasodilation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | claimed |
| EP-0344425-B1 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER LAMBERT CO (US) | 1993-12-08 | — | — | EP | claimed |
| US-5158959-A | Treatment of hypertension | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | claimed |
| EP-0344425-A2 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1989-12-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234081-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | C5, C9, C1R | CA12 1703/4885CA2 1487/4885CA9 1595/4885 |
| US-10609930-B2 | Methods and compositions for weed control | AS3MT, NOTUM, POLR1C | CA12 4365/4885CA2 2145/4885CA9 2313/4885 |
| US-10612019-B2 | Methods and compositions for weed control | NOTUM, LOXL3, CXXC5 | CA12 4076/4885CA2 2793/4885CA9 2181/4885 |
| US-20040009995-A1 | Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions | C5, C9, C1R | CA12 2821/4885CA2 2236/4885CA9 2912/4885 |
| US-20160029644-A1 | Methods and Compositions for Weed Control | AS3MT, NOTUM, POLR1C | CA12 4365/4885CA2 2145/4885CA9 2313/4885 |
| US-10568328-B2 | Methods and compositions for weed control | CYC1, PRDX5, CYCS | CA12 4207/4885CA2 1676/4885CA9 2647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.