Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 5/20 | 0.44 |
| ▸ | GSK3B | P49841 | 5/20 | 0.44 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | WRN | Q14191 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12852134 | 0.92 | GSK3A (0.38) | GSK3AGSK3BMGLLFAAHALDH1A1 | |
| SCHEMBL25849153 | 0.89 | GSK3A (0.53) | GSK3AGSK3BMGLLFAAHALDH1A1 | |
| SCHEMBL7098396 | 0.77 | MGLL (0.50) | GSK3AGSK3BMGLLFAAHALDH1A1 | |
| SCHEMBL3874763 | 0.77 | ALDH1A1 (0.63) | GSK3AGSK3BMGLLFAAHALDH1A1 | |
| SCHEMBL14984834 | 0.74 | PTGS1 (0.49) | GSK3AGSK3BMGLLFAAHALDH1A1 | |
| SCHEMBL5165325 | 0.74 | GSK3A (0.68) | GSK3AGSK3BMGLLFAAHALDH1A1 | |
| SCHEMBL996454 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1HSP90AA1TDP1 | |
| SCHEMBL23298275 | 0.73 | GSK3A (0.57) | GSK3AGSK3BMGLLALDH1A1MAPK1 | |
| SCHEMBL1230250 | 0.73 | ALDH1A1 (0.52) | GSK3AGSK3BMGLLFAAHALDH1A1 | |
| SCHEMBL5826261 | 0.72 | MGLL (0.46) | GSK3AGSK3BMGLLFAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007111606-A1 | RADIATION-OR THERMALLY-CURABLE BARRIER SEALANTS | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 2007-10-04 | — | — | WO | disclosed |