SCHEMBL3874763

SCHEMBL3874763

O=C(CCN1C(=O)C=CC1=O)OCN1C(=O)C=CC1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
HPGD P15428 2/20 0.63
CYP1A2 P05177 2/20 0.63
CYP2C19 P33261 2/20 0.63
BLM P54132 2/20 0.63
WRN Q14191 1/20 0.63
HIF1A Q16665 1/20 0.63
PTGS1 P23219 7/20 0.47
PTGS2 P35354 7/20 0.47
GSK3A P49840 2/20 0.47
GSK3B P49841 2/20 0.47
MGLL Q99685 7/20 0.46
FAAH O00519 3/20 0.46
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
HSP90AA1 P07900 1/20 0.45
TLR9 Q9NR96 1/20 0.45
TP53 P04637 1/20 0.45
PKM P14618 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7098396 0.88 MGLL (0.50) ALDH1A1HPGDCYP1A2CYP2C19BLM
SCHEMBL14984834 0.85 PTGS1 (0.49) ALDH1A1HPGDCYP1A2CYP2C19BLM
SCHEMBL5165325 0.85 GSK3A (0.68) ALDH1A1HPGDCYP1A2CYP2C19BLM
SCHEMBL1230250 0.83 ALDH1A1 (0.52) ALDH1A1HPGDCYP1A2CYP2C19BLM
SCHEMBL5826261 0.83 MGLL (0.46) ALDH1A1HPGDCYP1A2CYP2C19BLM
SCHEMBL31084132 0.82 CYP2C19 (0.61) ALDH1A1HPGDCYP1A2CYP2C19BLM
SCHEMBL12021170 0.82 MGLL (0.44) ALDH1A1HPGDCYP1A2CYP2C19BLM
SCHEMBL5160607 0.82 ALDH1A1 (0.51) ALDH1A1HPGDCYP1A2CYP2C19BLM
SCHEMBL4618418 0.82 ALDH1A1 (0.50) ALDH1A1HPGDCYP1A2CYP2C19BLM
SCHEMBL14014719 0.80 MGLL (0.43) ALDH1A1HPGDCYP1A2CYP2C19BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250042951-A1 PRE-FUSION RSV F ANTIGENS NOVARTIS AG (CH) 2025-02-06 US disclosed
US-20240239845-A1 PRE-FUSION RSV F ANTIGENS NOVARTIS AG (CH) 2024-07-18 US disclosed
CN-115003803-A Monomeric proteins and products for hydroxylated amino acids 现代牧场股份有限公司 2022-09-02 CN disclosed
EP-1856146-B1 FGF GROWTH FACTOR ANALOGS FERRING BV (NL) 2019-05-29 EP disclosed
US-8227411-B2 FGF growth factor analogs BioSurface Engineering Technologies, Incle (US) 2012-07-24 US disclosed
US-7528105-B1 Heterodimeric chain synthetic heparin-binding growth factor analogs BIOSURFACE ENGINEERING TECHNOLOGIES (US) 2009-05-05 US disclosed
US-20090111743-A1 Cysteine-branched heparin-binding growth factor analogs BIOSURFACE ENGINEERING TECHNOLOGIES, INC. (US) 2009-04-30 US disclosed
EP-1856146-A2 FGF GROWTH FACTOR ANALOGS Biosurface Engineering Technologies, Inc. (US) 2007-11-21 EP disclosed
WO-2006093814-A2 FGF GROWTH FACTOR ANALOGS BIOSURFACE ENGINEERING TECHNOLOGIES, INC. (US) 2006-09-08 WO disclosed
US-20060199764-A1 FGF growth factor analogs BIOSURFACE ENGINEERING TECHNOLOGIES, INC. (US) 2006-09-07 US disclosed
EP-1019371-B1 DIMALEINIMIDO-SUBSTITUTED DIHYDROXYALKANES WHICH CAN BE USED AS CROSSLINKING REAGENTS AND PROCESS FOR THEIR PREPARATION FORSCHUNGSZENTRUM JUELICH GMBH (DE) 2003-05-02 EP disclosed
US-5912359-A Dimaleinimido-substituted dihydroxyalkanes which can be used as crosslinking reagents and process for their preparation FORSCHUNGSZENTRUM JULICH GMBH (DE) 1999-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042951-A1 PRE-FUSION RSV F ANTIGENS FURIN, CD69, LY96 ALDH1A1 4643/4885HPGD 4028/4885CYP1A2 4859/4885
US-20240239845-A1 PRE-FUSION RSV F ANTIGENS FURIN, CD69, LY96 ALDH1A1 4643/4885HPGD 4028/4885CYP1A2 4859/4885
US-20090111743-A1 Cysteine-branched heparin-binding growth factor analogs HDGF, IGFBP1, IGFBP4 ALDH1A1 2571/4885HPGD 1708/4885CYP1A2 4737/4885
US-20060199764-A1 FGF growth factor analogs FGF2, FGF1, FGFR1 ALDH1A1 2944/4885HPGD 2343/4885CYP1A2 3822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.