Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25712302 | 0.83 | USP14 (0.57) | ALDH1A1MAPTNPSR1RAB9AHTT | |
| SCHEMBL9959370 | 0.81 | KMT2A (0.56) | ALDH1A1MAPTNPSR1RAB9AHTT | |
| SCHEMBL19298011 | 0.80 | USP14 (0.70) | — | |
| SCHEMBL984736 | 0.80 | EGFR (0.65) | ALDH1A1MAPTNPSR1HTTNPC1 | |
| SCHEMBL7278316 | 0.80 | EGFR (0.65) | ALDH1A1MAPTHTTL3MBTL1KMT2A | |
| SCHEMBL30443220 | 0.80 | EGFR (0.65) | ALDH1A1MAPTNPSR1HTTNPC1 | |
| SCHEMBL7277589 | 0.79 | KMT2A (0.52) | ALDH1A1MAPTNPSR1RAB9AHTT | |
| SCHEMBL7385787 | 0.79 | KMT2A (0.61) | ALDH1A1MAPTHTTNPC1SMN1; SMN2 | |
| SCHEMBL6671401 | 0.78 | EGFR (0.66) | ALDH1A1MAPTHTTL3MBTL1KMT2A | |
| SCHEMBL29414698 | 0.78 | EGFR (0.66) | ALDH1A1MAPTHTTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117180-A1 | AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) | 2007-10-18 | — | — | WO | disclosed |