Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276595 | 0.82 | ALDH1A1 (0.67) | KMT2AMEN1EGFRSRCALDH1A1 | |
| SCHEMBL14397448 | 0.79 | ALDH1A1 (0.67) | KMT2AMEN1EGFRSRCTSHR | |
| SCHEMBL7387785 | 0.78 | KMT2A (0.50) | KMT2AMEN1TSHRALDH1A1OXER1 | |
| SCHEMBL7278316 | 0.75 | EGFR (0.65) | KMT2AMEN1EGFRSRCALDH1A1 | |
| SCHEMBL984736 | 0.75 | EGFR (0.65) | KMT2AMEN1EGFRSRCALDH1A1 | |
| SCHEMBL30443220 | 0.75 | EGFR (0.65) | KMT2AMEN1EGFRSRCALDH1A1 | |
| SCHEMBL7275538 | 0.74 | TBXAS1 (0.53) | KMT2AMEN1TSHRALDH1A1L3MBTL1 | |
| SCHEMBL29414698 | 0.73 | EGFR (0.66) | KMT2AMEN1EGFRSRCALDH1A1 | |
| SCHEMBL6671401 | 0.73 | EGFR (0.66) | KMT2AMEN1EGFRSRCALDH1A1 | |
| SCHEMBL9959370 | 0.73 | KMT2A (0.56) | KMT2AMEN1EGFRSRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814344-A | ANTIEMENTICS, ANTIPSYCHOTICS | GLAXO GROUP LIMITED | 1989-03-21 | — | — | US | disclosed |
| EP-0266899-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1988-05-11 | — | — | EP | disclosed |