Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.52 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4378122 | 0.85 | HRH3 (0.54) | CARM1PRMT6PRMT8PRMT1HRH3 | |
| SCHEMBL4381194 | 0.84 | HRH3 (0.59) | CARM1PRMT6PRMT8SCN5AHRH3 | |
| SCHEMBL4375693 | 0.82 | CARM1 (0.54) | CARM1PRMT6PRMT8PRMT1HRH3 | |
| SCHEMBL17526224 | 0.82 | HRH3 (0.55) | CARM1PRMT6PRMT8SCN5AHRH3 | |
| SCHEMBL5911217 | 0.82 | HRH3 (0.62) | CARM1PRMT6PRMT8SCN5AHRH3 | |
| SCHEMBL10282578 | 0.81 | PRMT6 (0.55) | CARM1PRMT6PRMT8PRMT1HRH3 | |
| SCHEMBL13646385 | 0.80 | ACHE (0.56) | CARM1PRMT6PRMT8PRMT1HRH3 | |
| SCHEMBL4376306 | 0.80 | ACHE (0.56) | CARM1PRMT6PRMT8PRMT1HRH3 | |
| SCHEMBL5910693 | 0.80 | HRH3 (0.57) | CARM1PRMT6PRMT8SCN5AHRH3 | |
| SCHEMBL13661585 | 0.78 | HRH3 (0.56) | CARM1PRMT6PRMT8SCN5AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |