Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.56 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376306 | 1.00 | ACHE (0.56) | ACHECARM1PRMT6PRMT8PRMT1 | |
| SCHEMBL4383206 | 0.97 | CARM1 (0.58) | ACHECARM1PRMT6PRMT8PRMT1 | |
| SCHEMBL4373255 | 0.92 | CARM1 (0.58) | ACHECARM1PRMT6PRMT8PRMT1 | |
| SCHEMBL4378122 | 0.91 | HRH3 (0.54) | ACHECARM1PRMT6PRMT8PRMT1 | |
| SCHEMBL20234635 | 0.89 | CARM1 (0.65) | ACHECARM1PRMT6PRMT8PRMT1 | |
| SCHEMBL4375693 | 0.88 | CARM1 (0.54) | ACHECARM1PRMT6PRMT8PRMT1 | |
| SCHEMBL4374854 | 0.83 | CARM1 (0.54) | ACHECARM1PRMT6PRMT8PRMT1 | |
| SCHEMBL9192552 | 0.82 | ACHE (0.52) | ACHECARM1PRMT6PRMT8PRMT1 | |
| SCHEMBL9370937 | 0.81 | HRH3 (0.48) | ACHECARM1PRMT6PRMT8PRMT1 | |
| SCHEMBL14401649 | 0.80 | CARM1 (0.52) | ACHECARM1PRMT6PRMT8PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150065490-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2015-03-05 | — | — | US | disclosed |
| US-20150065490-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2015-03-05 | — | — | US | disclosed |
| EP-1529038-B1 | BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECEPTOR AGONIST ACTIVITY | NOVARTIS AG (CH) | 2009-10-07 | — | — | EP | disclosed |
| US-20070249586-A1 | Benzothiazole derivatives having beta-2-adrenoreceptor agonist activity | CUENOUD BERNARD | 2007-10-25 | — | — | US | disclosed |
| US-20070249586-A1 | Benzothiazole derivatives having beta-2-adrenoreceptor agonist activity | CUENOUD BERNARD | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249586-A1 | Benzothiazole derivatives having beta-2-adrenoreceptor agonist activity | ADRB2, ADRB1, ADRA2C | ACHE 838/4885CARM1 3814/4885PRMT6 4713/4885 |
| US-20150065490-A1 | ORGANIC COMPOUNDS | ADRB2, ADRA2C, ADRB1 | ACHE 534/4885CARM1 2947/4885PRMT6 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.