Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6758738 | 0.86 | PKM (0.33) | SMN1; SMN2PKMCNR1CNR2KMT2A | |
| SCHEMBL5411987 | 0.86 | ALDH1A1 (0.35) | SMN1; SMN2PKMCNR1CNR2KCNH2 | |
| SCHEMBL5383506 | 0.83 | PKM (0.44) | SMN1; SMN2PKMCNR1CNR2KCNH2 | |
| SCHEMBL1076637 | 0.83 | ALDH1A1 (0.37) | SMN1; SMN2PKMCNR1CNR2KMT2A | |
| SCHEMBL5420622 | 0.82 | NPC1 (0.34) | PKMCNR1CNR2KMT2AMAPT | |
| SCHEMBL2925238 | 0.80 | CNR1 (0.35) | SMN1; SMN2PKMCNR1CNR2KMT2A | |
| SCHEMBL14401656 | 0.77 | POLB (0.36) | SMN1; SMN2CNR1CNR2KCNH2KMT2A | |
| SCHEMBL14401659 | 0.77 | HTT (0.37) | SMN1; SMN2KCNH2KMT2AMEN1MAPT | |
| SCHEMBL1073892 | 0.76 | PKM (0.44) | SMN1; SMN2PKMMAPTPOLBHTT | |
| SCHEMBL5382948 | 0.76 | LMNA (0.49) | KMT2AMEN1MAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274286-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | The Procter & Gamble Company (US) | 2011-01-19 | — | — | EP | disclosed |
| US-7850742-B2 | Keratin dyeing compounds, keratin dyeing compositions containing said compounds, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2010-12-14 | — | — | US | disclosed |
| US-7850742-B2 | Keratin dyeing compounds, keratin dyeing compositions containing said compounds, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2010-12-14 | — | — | US | disclosed |
| US-7850742-B2 | Keratin dyeing compounds, keratin dyeing compositions containing said compounds, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2010-12-14 | — | — | US | disclosed |
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |
| US-20090282622-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Said Compounds, and Use Thereof | NOXELL CORPORATION | 2009-11-19 | — | — | US | disclosed |
| US-20090282622-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Said Compounds, and Use Thereof | NOXELL CORPORATION | 2009-11-19 | — | — | US | disclosed |
| US-20090282622-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Said Compounds, and Use Thereof | NOXELL CORPORATION | 2009-11-19 | — | — | US | disclosed |
| US-7285136-B2 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL, SA (FR) | 2007-10-23 | — | — | US | disclosed |
| US-20040103487-A1 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2004-06-03 | — | — | US | disclosed |
| EP-1362035-A1 | DIAMINOPYRAZOLE COMPOUNDS AND THE USE THEREOF IN THE OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002066441-A1 | DIAMINOPYRAZOLE COMPOUNDS AND THE USE THEREOF IN THE OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040103487-A1 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | KRT18, AOC1, DPYD | SMN1; SMN2 4615/4885PKM 232/4885CNR1 4402/4885 |
| US-20090282622-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Said Compounds, and Use Thereof | KRT18, TUBB3, PPOX | SMN1; SMN2 4796/4885PKM 99/4885CNR1 4671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.