Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 5/20 | 0.46 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.46 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099881 | 0.91 | SLC6A12 (0.50) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL1925986 | 0.88 | SLC6A12 (0.52) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL29697589 | 0.85 | SLC6A12 (0.50) | SLC6A12SLC6A11SLC6A13SMN1; SMN2SLC6A1 | |
| Bicarbonate SCHEMBL11401768 | 0.85 | CA1 (0.41) | CA1CA2CA4FFAR3HSD11B1 | |
| SCHEMBL11051978 | 0.83 | SLC6A12 (0.52) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL14361052 | 0.83 | CA1 (0.52) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL21974894 | 0.82 | CA1 (0.35) | CA1CA2CA4ALDH1A1 | |
| SCHEMBL3831316 | 0.79 | CA1 (0.31) | CA1CA2CA4 | |
| SCHEMBL2316031 | 0.79 | SLC6A12 (0.44) | SLC6A12SLC6A11SLC6A13AKR1C4AKR1C3 | |
| SCHEMBL11515327 | 0.78 | ALOX5 (0.39) | CA1CA2CA4FFAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074859-A | Indoleamine 2, the diaza and three aza-tricycle compounds of the cyclohexyl-ethyl substitution of 3 dioxygenases (IDO) antagonist are used as treating cancer | 默克专利有限公司 | 2017-08-18 | — | — | CN | disclosed |
| US-20070232549-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232549-A1 | Novel peptides as NS3-serine protease inhibitors of hepatitis C virus | HPN, TMPRSS15, VIP | SLC6A12 4805/4885SLC6A11 4766/4885SLC6A13 4656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.