Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.32 |
| ▸ | CA1 | P00915 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24538485 | 0.93 | LMNA (0.37) | CYP3A4MEN1KMT2ACA1FDPS | |
| SCHEMBL27412057 | 0.80 | LMNA (0.37) | CYP3A4MEN1KMT2A | |
| SCHEMBL19577892 | 0.80 | SIRT6 (0.32) | — | |
| SCHEMBL19578139 | 0.80 | KISS1R (0.40) | — | |
| SCHEMBL20435343 | 0.78 | SIRT6 (0.37) | CA2CA1 | |
| SCHEMBL22504504 | 0.78 | SLC15A1 (0.32) | ALDH1A1CYP3A4CA2CA1TSHR | |
| SCHEMBL25670865 | 0.78 | SLC15A1 (0.32) | ALDH1A1CYP3A4CA2CA1TSHR | |
| SCHEMBL23903091 | 0.78 | SIRT6 (0.37) | CA2CA1 | |
| SCHEMBL23128301 | 0.78 | HDAC4 (0.30) | — | |
| SCHEMBL25862564 | 0.78 | KISS1R (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016115168-A1 | INCORPORATION OF UNNATURAL NUCLEOTIDES AND METHODS THEREOF | Synthorx, Inc. (US) | 2016-07-21 | — | — | WO | disclosed |
| WO-2007115182-A2 | LINEAR NATRIURETIC PEPTIDE CONSTRUCTS | PALATIN TECHNOLOGIES, INC. (US) | 2007-10-11 | — | — | WO | disclosed |