Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5466704 | 0.77 | HSD11B1 (0.50) | HSD11B1ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL7829202 | 0.73 | HSD11B1 (0.50) | HSD11B1ALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL14403400 | 0.70 | HDAC3 (0.46) | ALDH1A1MAPTMEN1KMT2AMMP2 | |
| SCHEMBL2870934 | 0.69 | PSIP1 (0.54) | HSD11B1ALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL6803055 | 0.67 | HSD11B1 (0.50) | HSD11B1ALDH1A1LMNAL3MBTL1MMP13 | |
| SCHEMBL4230082 | 0.67 | PTGS1 (0.44) | — | |
| SCHEMBL14403403 | 0.67 | MMP2 (0.49) | MMP2 | |
| SCHEMBL1540593 | 0.66 | PSIP1 (0.56) | HSD11B1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL1722036 | 0.66 | PSIP1 (0.56) | HSD11B1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL9064967 | 0.66 | KYNU (0.65) | HSD11B1MMP13LARS1PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070248581-A1 | MGRA IS A REDOX REGULATOR OF ANTIBIOTIC SENSITIVITY AND VIRULENCE | THE UNIVERSITY OF CHICAGO | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070248581-A1 | MGRA IS A REDOX REGULATOR OF ANTIBIOTIC SENSITIVITY AND VIRULENCE | GFER, GLRX3, PRDX3 | HSD11B1 2834/4885ALDH1A1 3399/4885LMNA 4865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.