Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14404998 | 0.75 | CHRM2 (0.38) | CHRM2CHRM1CHRM4CHRM3CYP19A1 | |
| SCHEMBL9009430 | 0.69 | MEN1 (0.47) | MEN1KMT2ACYP3A4 | |
| SCHEMBL9009451 | 0.69 | MEN1 (0.47) | MEN1KMT2ACYP3A4 | |
| SCHEMBL31267268 | 0.69 | MEN1 (0.47) | MEN1KMT2ACYP3A4 | |
| SCHEMBL10125299 | 0.69 | MEN1 (0.47) | MEN1KMT2ACYP3A4 | |
| SCHEMBL15978072 | 0.67 | CHRM2 (0.40) | CHRM2CHRM1CHRM4CHRM3METAP2 | |
| SCHEMBL13410550 | 0.67 | CYP3A4 (0.46) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL7926060 | 0.67 | CHRM2 (0.48) | CHRM2CHRM1CHRM4CHRM3SLC18A3 | |
| SCHEMBL20995891 | 0.67 | CHRM2 (0.53) | CHRM2CHRM1CHRM4CHRM3SLC18A3 | |
| SCHEMBL789252 | 0.67 | CHRM2 (0.53) | CHRM2CHRM1CHRM4CHRM3SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700791-A | TREATMENT OF HYPERPROLIFERATIVE DISEASES OF THE SKIN | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-23 | — | — | US | disclosed |