Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.37 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309660 | 0.83 | IGF1R (0.47) | RECQLSMN1; SMN2ALDH1A1KDM4EIGF1R | |
| Hydrochloric Acid SCHEMBL2207439 | 0.82 | IGF1R (0.47) | RECQLSMN1; SMN2ALDH1A1KDM4EIGF1R | |
| SCHEMBL14406642 | 0.81 | ALDH1A1 (0.43) | RECQLSMN1; SMN2ALDH1A1L3MBTL3L3MBTL1 | |
| SCHEMBL14406661 | 0.81 | SIRT6 (0.56) | RECQLSMN1; SMN2ALDH1A1GAAPOLB | |
| SCHEMBL311522 | 0.81 | RECQL (0.44) | RECQLSMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10290706 | 0.80 | L3MBTL1 (0.60) | ALDH1A1L3MBTL3L3MBTL1GAAMBTD1 | |
| SCHEMBL25139814 | 0.77 | POLB (0.41) | RECQLSMN1; SMN2ALDH1A1KDM4EIGF1R | |
| SCHEMBL30043543 | 0.77 | POLB (0.41) | RECQLSMN1; SMN2ALDH1A1KDM4EIGF1R | |
| SCHEMBL25337128 | 0.76 | POLB (0.47) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL14980795 | 0.75 | TTK (0.46) | RECQLSMN1; SMN2ALDH1A1KDM4EIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162454-B1 | IMIDAZOPYRIDINE KINASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-01-02 | — | — | EP | disclosed |