Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5361040 | 1.00 | PIN1 (0.37) | PIN1APPHIF1APDE4APDE4B | |
| SCHEMBL3924177 | 1.00 | PIN1 (0.37) | PIN1APPHIF1APDE4APDE4B | |
| SCHEMBL14408050 | 1.00 | PIN1 (0.37) | PIN1APPHIF1APDE4APDE4B | |
| SCHEMBL3669336 | 0.85 | PIN1 (0.39) | PIN1APPHIF1APDE4APDE4B | |
| SCHEMBL3668993 | 0.85 | PIN1 (0.39) | PIN1APPHIF1APDE4APDE4B | |
| SCHEMBL14380399 | 0.84 | MEN1 (0.42) | APPHIF1APDE4APDE4BPDE4C | |
| SCHEMBL14626184 | 0.83 | SLC5A2 (0.35) | HIF1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14415238 | 0.83 | SLC5A2 (0.35) | HIF1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4620243 | 0.83 | SIRT1 (0.38) | PIN1APPCYP4F2CYP4A11BCHE | |
| SCHEMBL14408042 | 0.83 | APP (0.39) | PIN1APPHIF1APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268240-B2 | Synthetic methods for polyphenols | MARS, INC. | 2007-09-11 | — | — | US | disclosed |