Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924177 | 1.00 | PIN1 (0.37) | PIN1APPHIF1APDE4APDE4B | |
| SCHEMBL14408050 | 1.00 | PIN1 (0.37) | PIN1APPHIF1APDE4APDE4B | |
| SCHEMBL14408048 | 1.00 | PIN1 (0.37) | PIN1APPHIF1APDE4APDE4B | |
| SCHEMBL3669336 | 0.85 | PIN1 (0.39) | PIN1APPHIF1APDE4APDE4B | |
| SCHEMBL3668993 | 0.85 | PIN1 (0.39) | PIN1APPHIF1APDE4APDE4B | |
| SCHEMBL14380399 | 0.84 | MEN1 (0.42) | APPHIF1APDE4APDE4BPDE4C | |
| SCHEMBL14626184 | 0.83 | SLC5A2 (0.35) | HIF1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14415238 | 0.83 | SLC5A2 (0.35) | HIF1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4620243 | 0.83 | SIRT1 (0.38) | PIN1APPCYP4F2CYP4A11BCHE | |
| SCHEMBL14408042 | 0.83 | APP (0.39) | PIN1APPHIF1APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268240-B2 | Synthetic methods for polyphenols | MARS, INC. | 2007-09-11 | — | — | US | disclosed |
| US-20050277600-A1 | Compositions and methods of use of dimer digallates | MARS, INCROPORATED (US) | 2005-12-15 | — | — | US | disclosed |
| US-6849746-B2 | Synthetic methods for polyphenols | MARS, INC. (US) | 2005-02-01 | — | — | US | disclosed |
| US-20040235941-A1 | Dimer digallate compositions | MARS, INCORPORATED | 2004-11-25 | — | — | US | disclosed |
| US-20040236123-A1 | Synthetic methods for polyphenols | M&M/MARS INC. | 2004-11-25 | — | — | US | disclosed |
| US-20030176620-A1 | Synthetic methods for polyphenols | MARS INCORPORATED | 2003-09-18 | — | — | US | disclosed |
| US-6528664-B2 | Synthetic methods for polyphenols | MARS, INCORPORATED | 2003-03-04 | — | — | US | disclosed |
| EP-1027345-B1 | SYNTHETIC METHODS FOR POLYPHENOLS | MARS INC (US) | 2003-02-19 | — | — | EP | disclosed |
| US-20020128493-A1 | Coupling flavonoid-like compounds having protected hydroxy groups by functionalizing the C-4; oxidative dehydrogenation to form dimers and oligomers; efficiency; anticarciogenic agents; breast cancer | MARS, INCORPORATED | 2002-09-12 | — | — | US | disclosed |
| US-6420572-B1 | FLAVANOID DERIVATIVES AND PHENOLIC DERIVATIVES WITH HALOGENATION | MARS, INCORPORATED | 2002-07-16 | — | — | US | disclosed |
| US-6207842-B1 | FROM EPICATECHIN | MARS INCORPORATED | 2001-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236123-A1 | Synthetic methods for polyphenols | MLN, NQO1, NOD2 | PIN1 614/4885APP 1649/4885HIF1A 2355/4885 |
| US-20020128493-A1 | Coupling flavonoid-like compounds having protected hydroxy groups by functionalizing the C-4; oxidative dehydrogenation to form dimers and oligomers; efficiency; anticarciogenic agents; breast cancer | GPX4, NOX4, TPD52L2 | PIN1 1950/4885APP 3658/4885HIF1A 1169/4885 |
| US-20040235941-A1 | Dimer digallate compositions | NOD2, GID4, GPX4 | PIN1 273/4885APP 2930/4885HIF1A 1553/4885 |
| US-20050277600-A1 | Compositions and methods of use of dimer digallates | FABP3, FGB, F2 | PIN1 3984/4885APP 662/4885HIF1A 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.