Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
| ▸ | CHRNA2 | Q15822 | 3/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4144285 | 0.95 | SLC6A2 (0.36) | GHSR | |
| SCHEMBL23903228 | 0.89 | GHSR (0.33) | CHRNB4CHRNA3GHSR | |
| SCHEMBL26618361 | 0.82 | CYP2D6 (0.41) | GHSR | |
| SCHEMBL26618343 | 0.82 | CYP2D6 (0.41) | GHSR | |
| SCHEMBL4520902 | 0.81 | CHRNB2 (0.35) | CHRNB2CHRNA4CHRNB4CHRNA3GHSR | |
| SCHEMBL25562847 | 0.80 | FDPS (0.34) | CHRNB4CHRNA3GHSR | |
| SCHEMBL18360656 | 0.80 | FDPS (0.34) | CHRNB4CHRNA3GHSR | |
| SCHEMBL4146408 | 0.76 | CYP2D6 (0.35) | GHSR | |
| SCHEMBL9121250 | 0.76 | CYP2D6 (0.40) | CHRNB2CHRNA4GHSR | |
| SCHEMBL4158323 | 0.76 | CYP2D6 (0.40) | CHRNB2CHRNA4GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474419-B1 | AMIDES OF AMINOALKYL-SUBSTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES | NOVO NORDISK AS (DK) | 2007-09-05 | — | — | EP | disclosed |