Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
| ▸ | GHSR | Q92847 | 6/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25562847 | 1.00 | FDPS (0.34) | FDPSGHSRSSTR2CHRNB4CHRNA3 | |
| SCHEMBL9874777 | 0.95 | FDPS (0.40) | FDPSGHSRSSTR2 | |
| SCHEMBL9875342 | 0.95 | FDPS (0.40) | FDPSGHSRSSTR2 | |
| SCHEMBL23903228 | 0.83 | GHSR (0.33) | FDPSGHSRCHRNB4CHRNA3 | |
| SCHEMBL14409478 | 0.80 | PRCP (0.33) | GHSRCHRNB4CHRNA3 | |
| SCHEMBL17484303 | 0.79 | FDPS (0.42) | FDPSGHSR | |
| SCHEMBL28871650 | 0.79 | FDPS (0.39) | FDPSGHSR | |
| SCHEMBL5046004 | 0.79 | CYP1A2 (0.45) | FDPSGHSR | |
| SCHEMBL4520902 | 0.79 | CHRNB2 (0.35) | FDPSGHSRCHRNB4CHRNA3 | |
| SCHEMBL18357174 | 0.77 | FDPS (0.35) | FDPSGHSRCHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076448-A1 | SOMATOSTATIN MODULATORS FOR TREATING PITUITARY ADENOMAS | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |
| EP-3317277-B1 | SOMATOSTATIN MODULATORS AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2021-01-20 | — | — | EP | disclosed |
| WO-2017003723-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2017-01-05 | — | — | WO | disclosed |