Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP3 | Q92482 | 1/20 | 0.48 |
| ▸ | AQP1 | P29972 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681480 | 0.87 | AQP3 (0.50) | AQP3AQP1HRH1SIGMAR1CHRM2 | |
| SCHEMBL13503985 | 0.84 | AQP3 (0.47) | AQP3AQP1HRH1SIGMAR1CHRM2 | |
| Bencyclane SCHEMBL64881 | 0.83 | AQP3 (0.44) | AQP3AQP1HRH1SIGMAR1CHRM2 | |
| SCHEMBL11666639 | 0.77 | AQP1 (0.43) | AQP3AQP1HRH1CHRM2CHRM1 | |
| SCHEMBL13504042 | 0.76 | AQP3 (0.55) | AQP3AQP1HRH1CHRM2CHRM1 | |
| Bencyclane SCHEMBL220903 | 0.75 | HRH1 (0.52) | AQP3AQP1HRH1CHRM2CHRM1 | |
| Bencyclane SCHEMBL1568812 | 0.75 | HRH1 (0.52) | AQP3AQP1HRH1CHRM2CHRM1 | |
| SCHEMBL11444307 | 0.74 | HRH3 (0.50) | AQP3SIGMAR1CHRM2CHRM1HRH3 | |
| Bencyclane SCHEMBL20505617 | 0.74 | HRH1 (0.51) | AQP3AQP1HRH1CHRM2CHRM1 | |
| SCHEMBL7780678 | 0.69 | SLC6A1 (0.56) | AQP3AQP1HRH1SIGMAR1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487811-B1 | N-SULFONYLUREA APOPTOSIS PROMOTERS | ABBOTT LAB (US) | 2007-09-05 | — | — | EP | disclosed |