Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14809680 | 0.73 | PGK1 (0.39) | PDXKAGTR1AGTR2HTT | |
| SCHEMBL5057521 | 0.72 | AURKA (0.38) | PDXKAGTR1AGTR2HTT | |
| SCHEMBL1521623 | 0.71 | HTT (0.55) | AGTR1AGTR2HTT | |
| SCHEMBL4713441 | 0.66 | AURKA (0.51) | HTT | |
| SCHEMBL22866260 | 0.62 | STK17B (0.39) | PDXKAGTR1AGTR2HTT | |
| SCHEMBL14410874 | 0.62 | TLR8 (0.31) | — | |
| SCHEMBL7520889 | 0.62 | CDK1 (0.31) | — | |
| SCHEMBL8460756 | 0.62 | PDE2A (0.33) | — | |
| SCHEMBL20189663 | 0.61 | PDE2A (0.33) | — | |
| SCHEMBL20189661 | 0.61 | PDE2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539755-B1 | 6-ALKOXY-PYRIDO-PYRIMIDINES AS P-38 MAP KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-09-26 | — | — | EP | disclosed |