Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.79 |
| ▸ | THRB | P10828 | 2/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PTPRA | P18433 | 1/20 | 0.61 |
| ▸ | PTPRB | P23467 | 1/20 | 0.61 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.51 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112146 | 0.96 | CYP1A2 (0.85) | CYP2C9CYP1A2THRBHIF1ACYP2C19 | |
| SCHEMBL14418343 | 0.96 | CYP1A2 (0.85) | CYP2C9CYP1A2THRBHIF1ACYP2C19 | |
| SCHEMBL30940027 | 0.96 | CYP1A2 (0.85) | CYP2C9CYP1A2THRBHIF1ACYP2C19 | |
| SCHEMBL142459 | 0.96 | CYP1A2 (0.85) | CYP2C9CYP1A2THRBHIF1ACYP2C19 | |
| SCHEMBL628908 | 0.96 | CYP1A2 (0.85) | CYP2C9CYP1A2THRBHIF1ACYP2C19 | |
| SCHEMBL142457 | 0.95 | CYP1A2 (0.83) | CYP2C9CYP1A2THRBHIF1ACYP2C19 | |
| SCHEMBL30486026 | 0.95 | CYP1A2 (0.83) | CYP2C9CYP1A2THRBHIF1ACYP2C19 | |
| SCHEMBL4808250 | 0.95 | CYP1A2 (0.83) | CYP2C9CYP1A2THRBHIF1ACYP2C19 | |
| SCHEMBL28291310 | 0.95 | CYP1A2 (0.83) | CYP2C9CYP1A2THRBHIF1ACYP2C19 | |
| SCHEMBL5321833 | 0.91 | CYP2C9 (0.81) | CYP2C9CYP1A2THRBHIF1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7264932-B2 | Nuclease inhibitor cocktail | APPLERA CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |
| US-7264932-B2 | Nuclease inhibitor cocktail | APPLERA CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |
| US-20070032418-A1 | Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same | AMBION, INC (US) | 2007-02-08 | — | — | US | disclosed |
| US-20070032418-A1 | Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same | AMBION, INC (US) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032418-A1 | Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same | RNASE1, RNASEH1, RNASEL | CYP2C9 4801/4885CYP1A2 4375/4885THRB 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.