Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUMO2 | P61956 | 2/20 | 0.86 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.86 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.86 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.86 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.86 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.86 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952032 | 1.00 | SUMO2 (0.86) | SUMO2SUMO1SENP7SENP2SENP3 | |
| SCHEMBL29637786 | 0.99 | SUMO2 (0.84) | SUMO2SUMO1SENP7SENP2SENP3 | |
| SCHEMBL14418340 | 0.98 | SUMO2 (0.83) | SUMO2SUMO1SENP7SENP2SENP3 | |
| SCHEMBL19132261 | 0.95 | SENP2 (0.78) | SUMO2SUMO1SENP7SENP2SENP3 | |
| SCHEMBL29374866 | 0.93 | SUMO2 (1.00) | SUMO2SUMO1SENP7SENP2SENP3 | |
| SCHEMBL14418523 | 0.93 | SUMO2 (1.00) | SUMO2SUMO1SENP7SENP2SENP3 | |
| SCHEMBL14613567 | 0.92 | SUMO2 (0.74) | SUMO2SUMO1SENP7SENP2SENP3 | |
| SCHEMBL14418372 | 0.91 | SUMO2 (0.72) | SUMO2SUMO1SENP7SENP2SENP3 | |
| SCHEMBL12534468 | 0.88 | SUMO2 (0.69) | SUMO2SUMO1SENP7SENP2SENP3 | |
| SCHEMBL14583209 | 0.86 | SUMO2 (0.67) | SUMO2SUMO1SENP7SENP2SENP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7264932-B2 | Nuclease inhibitor cocktail | APPLERA CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |
| US-7264932-B2 | Nuclease inhibitor cocktail | APPLERA CORPORATION (US) | 2007-09-04 | — | — | US | disclosed |