SCHEMBL4952032

SCHEMBL4952032

Cc1cc(-c2ccc(N=Nc3c(N)ccc4cc(S(=O)(=O)O)ccc34)c(C)c2)ccc1N=Nc1c(N)ccc2cc(S(=O)(=O)O)ccc12

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SUMO2 P61956 2/20 0.86
▸ SUMO1 P63165 2/20 0.86
▸ SENP7 Q9BQF6 2/20 0.86
▸ SENP2 Q9HC62 2/20 0.86
▸ SENP3 Q9H4L4 1/20 0.86
▸ SENP1 Q9P0U3 1/20 0.86
▸ ENPP2 Q13822 7/20 0.64
▸ MEN1 O00255 3/20 0.61
▸ KMT2A Q03164 3/20 0.61
▸ HTT P42858 1/20 0.61
▸ ALDH1A1 P00352 3/20 0.58
▸ HIF1A Q16665 2/20 0.58
▸ PHLPP2 Q6ZVD8 2/20 0.54
▸ CYP2C9 P11712 5/20 0.52
▸ CYP2C19 P33261 4/20 0.52
▸ HSD17B10 Q99714 4/20 0.52
▸ TSHR P16473 2/20 0.52
▸ THRB P10828 2/20 0.52
▸ KDM4E B2RXH2 1/20 0.52
▸ TP53 P04637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14413371 1.00 SUMO2 (0.86) SUMO2SUMO1SENP7SENP2SENP3
SCHEMBL29637786 0.99 SUMO2 (0.84) SUMO2SUMO1SENP7SENP2SENP3
SCHEMBL14418340 0.98 SUMO2 (0.83) SUMO2SUMO1SENP7SENP2SENP3
SCHEMBL19132261 0.95 SENP2 (0.78) SUMO2SUMO1SENP7SENP2SENP3
SCHEMBL29374866 0.93 SUMO2 (1.00) SUMO2SUMO1SENP7SENP2SENP3
SCHEMBL14418523 0.93 SUMO2 (1.00) SUMO2SUMO1SENP7SENP2SENP3
SCHEMBL14613567 0.92 SUMO2 (0.74) SUMO2SUMO1SENP7SENP2SENP3
SCHEMBL14418372 0.91 SUMO2 (0.72) SUMO2SUMO1SENP7SENP2SENP3
SCHEMBL12534468 0.88 SUMO2 (0.69) SUMO2SUMO1SENP7SENP2SENP3
SCHEMBL14583209 0.86 SUMO2 (0.67) SUMO2SUMO1SENP7SENP2SENP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240167107-A1 COMPOSITION AND METHOD FOR NUCLEIC ACID DETECTION APTITUDE MEDICAL SYSTEMS, INC. (US) 2024-05-23 — — US claimed
US-7264932-B2 Nuclease inhibitor cocktail APPLERA CORPORATION (US) 2007-09-04 — — US claimed
WO-2005083081-A1 IMPROVED NUCLEASE INHIBITOR COCKTAIL AMBION, INC. (US) 2005-09-09 — — WO claimed
US-20050014169-A1 Nuclease inhibitor cocktail AMBION, INC. 2005-01-20 — — US claimed
US-20240167107-A1 COMPOSITION AND METHOD FOR NUCLEIC ACID DETECTION APTITUDE MEDICAL SYSTEMS, INC. (US) 2024-05-23 — — US disclosed
US-20170205669-A1 IMAGE DISPLAY DEVICE AND ORIENTED MATERIAL USED IN SAME DIC CORPORATION (JP) 2017-07-20 — — US disclosed
WO-2008157747-A1 USE OF INHIBITION OF EXONUCLEASE 1 IN METHODS FOR THERAPY AND DIAGNOSTIC OF NEURODEGENERATIVE DISEASES, EYE DISEASES, AND MITOCHONDRIAL DISORDERS THE JACKSON LABORATORY (US) 2008-12-24 — — WO disclosed
US-7264932-B2 Nuclease inhibitor cocktail APPLERA CORPORATION (US) 2007-09-04 — — US disclosed
WO-2005083081-A1 IMPROVED NUCLEASE INHIBITOR COCKTAIL AMBION, INC. (US) 2005-09-09 — — WO disclosed
US-20050014169-A1 Nuclease inhibitor cocktail AMBION, INC. 2005-01-20 — — US disclosed
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