SCHEMBL19132261

SCHEMBL19132261

Cc1cc(-c2ccc(N=Nc3c(N)ccc4cc(S(=O)(=O)O)ccc34)c(C)c2)ccc1N=Nc1c(N)ccc2ccccc12

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SENP2 Q9HC62 5/20 0.78
▸ SENP1 Q9P0U3 5/20 0.78
▸ SENP3 Q9H4L4 4/20 0.78
▸ SUMO2 P61956 3/20 0.78
▸ SUMO1 P63165 3/20 0.78
▸ SENP7 Q9BQF6 3/20 0.78
▸ ENPP2 Q13822 3/20 0.67
▸ PHLPP2 Q6ZVD8 2/20 0.57
▸ HIF1A Q16665 3/20 0.56
▸ CYP1A2 P05177 3/20 0.56
▸ TSHR P16473 3/20 0.56
▸ HSD17B10 Q99714 3/20 0.56
▸ CYP2C9 P11712 3/20 0.56
▸ CYP2C19 P33261 2/20 0.56
▸ PTPRA P18433 1/20 0.56
▸ PTPRB P23467 1/20 0.56
▸ RAPGEF4 Q8WZA2 1/20 0.56
▸ MEN1 O00255 3/20 0.56
▸ KMT2A Q03164 3/20 0.56
▸ HTT P42858 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14413371 0.95 SUMO2 (0.86) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL4952032 0.95 SUMO2 (0.86) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL29637786 0.94 SUMO2 (0.84) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL14418340 0.93 SUMO2 (0.83) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL14418523 0.88 SUMO2 (1.00) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL29374866 0.88 SUMO2 (1.00) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL14613567 0.87 SUMO2 (0.74) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL14418372 0.86 SUMO2 (0.72) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL12534468 0.84 SUMO2 (0.69) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL6267501 0.83 SENP2 (0.65) SENP2SENP1SENP3SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170205669-A1 IMAGE DISPLAY DEVICE AND ORIENTED MATERIAL USED IN SAME DIC CORPORATION (JP) 2017-07-20 — — US disclosed
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