Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361593 | 0.84 | RAB9A (0.66) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL12994636 | 0.83 | TSHR (0.71) | ALDH1A1LMNAEPHX2MAPTNPC1 | |
| SCHEMBL11839197 | 0.82 | SMN1; SMN2 (0.68) | ALDH1A1LMNAEPHX2MAPTNPC1 | |
| SCHEMBL11837576 | 0.82 | ALOX5 (0.69) | ALDH1A1LMNAEPHX2MAPTNPC1 | |
| SCHEMBL11833345 | 0.81 | LMNA (0.79) | ALDH1A1LMNAEPHX2MAPTNPC1 | |
| SCHEMBL22217937 | 0.81 | GAA (0.68) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL12668447 | 0.81 | LMNA (0.64) | ALDH1A1LMNAEPHX2MAPTNPC1 | |
| SCHEMBL13450335 | 0.79 | MEN1 (0.68) | ALDH1A1LMNAEPHX2MAPTNPC1 | |
| SCHEMBL5912255 | 0.79 | TRPV1 (0.70) | ALDH1A1LMNAMAPTNPC1KDM4E | |
| SCHEMBL14393776 | 0.78 | EPHX2 (0.70) | ALDH1A1LMNAEPHX2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106706-A1 | CYCLIC UREA COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS EFFECTIVE FOR THE TREATMENT OF CARDIOVASCULAR DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-09-20 | — | — | WO | disclosed |