Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.40 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.38 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.38 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.38 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14415074 | 0.93 | HCAR2 (0.40) | APPHCAR2AKR1C3AKR1C2THRA | |
| SCHEMBL14415084 | 0.93 | HCAR2 (0.40) | APPHCAR2AKR1C3AKR1C2THRA | |
| SCHEMBL14415075 | 0.93 | HCAR2 (0.40) | APPHCAR2AKR1C3AKR1C2THRA | |
| SCHEMBL19999162 | 0.77 | ALOX15 (0.59) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL6741191 | 0.76 | ALOX15 (0.52) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL14415091 | 0.76 | THRB (0.45) | KDM4EMEN1KMT2ATHRB | |
| SCHEMBL14415076 | 0.75 | TSHR (0.49) | APPTHRATHRB | |
| SCHEMBL14282663 | 0.75 | APP (0.40) | APPHCAR2AKR1C3AKR1C2THRA | |
| SCHEMBL14282661 | 0.74 | HTR1A (0.45) | ALOX15AKR1C3ELANEKDM4E | |
| SCHEMBL14282664 | 0.74 | HTR1A (0.45) | ALOX15AKR1C3ELANEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273641-B2 | Optically anisotropic element comprising discotic compound | FUJIFILM CORPORATION (JP) | 2007-09-25 | — | — | US | disclosed |