Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14415077 | 0.88 | HDAC10 (0.42) | ALDH1A1LMNASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL14415086 | 0.84 | MEN1 (0.38) | MEN1KMT2AFFAR1 | |
| SCHEMBL14415084 | 0.81 | HCAR2 (0.40) | THRB | |
| SCHEMBL14415075 | 0.81 | HCAR2 (0.40) | THRB | |
| SCHEMBL14415074 | 0.81 | HCAR2 (0.40) | THRB | |
| SCHEMBL14282677 | 0.78 | THRB (0.49) | THRBALDH1A1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL14282668 | 0.78 | TP53 (0.41) | SMN1; SMN2KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL14415092 | 0.76 | ALOX15 (0.42) | THRBMEN1KMT2AKDM4E | |
| SCHEMBL14415088 | 0.75 | ALDH1A1 (0.55) | ALDH1A1 | |
| SCHEMBL7594187 | 0.75 | ABCG2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273641-B2 | Optically anisotropic element comprising discotic compound | FUJIFILM CORPORATION (JP) | 2007-09-25 | — | — | US | disclosed |
| US-7273641-B2 | Optically anisotropic element comprising discotic compound | FUJIFILM CORPORATION (JP) | 2007-09-25 | — | — | US | disclosed |