Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13470151 | 0.88 | CYP11B1 (0.49) | CYP11B1CYP11B2HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL8971686 | 0.85 | CYP11B1 (0.68) | CYP11B1CYP11B2HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL6599807 | 0.82 | CYP11B1 (0.55) | CYP11B1CYP11B2HTTIDO1ADORA2A | |
| Hydrochloric Acid SCHEMBL6599039 | 0.81 | CYP11B1 (0.50) | CYP11B1CYP11B2HTTIDO1ADORA2A | |
| SCHEMBL6180585 | 0.79 | CYP11B1 (0.44) | CYP11B1CYP11B2HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL531371 | 0.76 | CYP11B1 (0.73) | CYP11B1CYP11B2CYP2A6IDO1MAOA | |
| SCHEMBL14465623 | 0.76 | CYP2C9 (0.35) | CYP11B1CYP11B2ADORA2A | |
| SCHEMBL8862697 | 0.75 | CYP11B1 (0.51) | CYP11B1CYP11B2IDO1SIGMAR1POLB | |
| Trifluoroacetic Acid SCHEMBL5880541 | 0.75 | CYP11B1 (0.58) | CYP11B1CYP11B2IDO1FNTAFNTB | |
| SCHEMBL6989844 | 0.75 | TSHR (0.48) | CYP11B1CYP11B2HTTIDO1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213340-A1 | Farnesyl protein transferase inhibitors | SCHERING CORPORATION | 2007-09-13 | — | — | US | disclosed |
| US-20070213340-A1 | Farnesyl protein transferase inhibitors | SCHERING CORPORATION | 2007-09-13 | — | — | US | disclosed |
| WO-2007084498-A1 | PIPERAZINE DERIVATIVES AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213340-A1 | Farnesyl protein transferase inhibitors | FNTB, FNTA, FDPS | CYP11B1 1991/4885CYP11B2 2663/4885HTR2A 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.