Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10311847 | 0.83 | TSHR (0.44) | TSHRCNR1ALDH1A1LMNAKDM4E | |
| SCHEMBL15760615 | 0.81 | EPHX2 (0.35) | TSHRCNR1EPHX2ALDH1A1RECQL | |
| SCHEMBL13296416 | 0.80 | TSHR (0.50) | TSHRCNR1ALDH1A1RECQLABCB11 | |
| SCHEMBL10311846 | 0.80 | TSHR (0.59) | TSHRCNR1ALDH1A1LMNAKDM4E | |
| SCHEMBL15773187 | 0.80 | CYP2C19 (0.38) | TSHRNAMPTEPHX2ALDH1A1RECQL | |
| SCHEMBL17154348 | 0.80 | TSHR (0.51) | TSHRCNR1EPHX2ALDH1A1RECQL | |
| SCHEMBL29330872 | 0.80 | KDM4E (0.46) | TSHRNAMPTCNR1ALDH1A1KDM4E | |
| SCHEMBL16241868 | 0.79 | TSHR (0.50) | TSHRNAMPTALDH1A1RECQLLMNA | |
| SCHEMBL22473787 | 0.79 | FAAH (0.57) | TSHRCNR1EPHX2RECQLFAAH | |
| SCHEMBL14685798 | 0.79 | GLP1R (0.47) | TSHRCNR1RECQLABCB11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273909-B2 | Polyethylene glycol aldehydes | HOFFMANN-LA ROCHE INC. (US) | 2007-09-25 | — | — | US | disclosed |
| US-20070167606-A1 | Polyethylene glycol aldehydes | WON CHEE-YOUB | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167606-A1 | Polyethylene glycol aldehydes | ALDH2, ADH5, ADH1A | TSHR 4360/4885NAMPT 1028/4885CNR1 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.