SCHEMBL14417554

SCHEMBL14417554

COc1ccc(C[C@@H]2CCCN2)cc1

nearest known ligand 0.71

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.56
LTA4H P09960 2/20 0.49
HTR6 P50406 1/20 0.48
ALDH1A1 P00352 1/20 0.48
CHRNB4 P30926 1/20 0.48
CHRNA3 P32297 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3167638 1.00 POLB (0.56) POLBLTA4HHTR6ALDH1A1CHRNB4
Hydrochloric Acid SCHEMBL11373827 0.98 POLB (0.54) POLBLTA4HHTR6ALDH1A1CHRNB4
SCHEMBL18019872 0.95 POLB (0.63) POLBLTA4HALDH1A1
SCHEMBL18019867 0.95 POLB (0.63) POLBLTA4HALDH1A1
SCHEMBL20109499 0.95 POLB (0.63) POLBLTA4HALDH1A1
Hydrochloric Acid SCHEMBL7155487 0.94 POLB (0.61) POLBLTA4HALDH1A1
SCHEMBL11486260 0.94 POLB (0.61) POLBLTA4HALDH1A1
Oxalic Acid SCHEMBL1443439 0.91 POLB (0.51) POLBLTA4HHTR6ALDH1A1
SCHEMBL23255157 0.88 ALDH1A1 (0.48) ALDH1A1
SCHEMBL23255515 0.88 ALDH1A1 (0.48) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2023-11-02 US disclosed
US-7265145-B2 Substituted piperidines and pyrrolidines as calcium sensing receptor modulators and method BRISTOL-MYERS SQUIBB COMPANY (US) 2007-09-04 US disclosed
US-7265145-B2 Substituted piperidines and pyrrolidines as calcium sensing receptor modulators and method BRISTOL-MYERS SQUIBB COMPANY (US) 2007-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION POLRMT, DCLRE1B, RNGTT POLB 8/4885LTA4H 3440/4885HTR6 3520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.