Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417851 | 0.89 | ALDH1A1 (0.38) | ATML3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL14417850 | 0.85 | ATM (0.47) | ATML3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL19769254 | 0.83 | GNAI3 (0.43) | ATML3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL30619169 | 0.82 | L3MBTL1 (0.56) | ATML3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL19769294 | 0.81 | L3MBTL1 (0.39) | ATML3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL14417859 | 0.78 | VNN1 (0.36) | NPC1MEN1KMT2ATDP1LMNA | |
| SCHEMBL14417860 | 0.75 | VNN1 (0.37) | USP2ALDH1A1CYP3A4VNN1ITGB3 | |
| SCHEMBL1290779 | 0.75 | VNN1 (0.38) | NPC1ALDH1A1VNN1 | |
| SCHEMBL14417843 | 0.75 | CYP1A2 (0.43) | MEN1KMT2ATDP1KDM4EUSP2 | |
| SCHEMBL19769253 | 0.75 | MEN1 (0.47) | L3MBTL1NPC1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268150-B2 | 2-cyano-4-fluoropyrrolidine derivative or its salt | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-11 | — | — | US | disclosed |
| US-7268150-B2 | 2-cyano-4-fluoropyrrolidine derivative or its salt | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-11 | — | — | US | disclosed |