Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419319 | 0.79 | ABCC9 (0.43) | KMT2AMEN1ABCC9ABCC8KCNJ11 | |
| SCHEMBL4029409 | 0.77 | ABCC9 (0.48) | KMT2AABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8017713 | 0.77 | KMT2A (0.62) | KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL11046642 | 0.75 | GAA (0.52) | KMT2AMEN1ABCC9ABCC8KCNJ11 | |
| SCHEMBL14419314 | 0.73 | TXNRD1 (0.57) | KMT2AMEN1MAPTPAX8TSHR | |
| SCHEMBL2478404 | 0.72 | KMT2A (0.56) | KMT2AMEN1ABCC9ABCC8KCNJ11 | |
| SCHEMBL6516381 | 0.71 | MAPT (0.53) | KMT2AMEN1MAPTTSHRHPGD | |
| SCHEMBL14419317 | 0.70 | FBP1 (0.42) | KMT2AMEN1MAPTTSHRKDM4E | |
| SCHEMBL11745901 | 0.70 | TSHR (0.54) | KMT2AMEN1MAPTTSHRKDM4E | |
| SCHEMBL1828638 | 0.70 | MAPT (0.51) | MAPTTSHRVCAM1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |