Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14419318 | 0.79 | KMT2A (0.42) | ABCC9ABCC8KCNJ11KCNJ8NAMPT | |
| SCHEMBL4037249 | 0.78 | LMNA (0.55) | ABCC9ABCC8KCNJ11KCNJ8NAMPT | |
| SCHEMBL11046642 | 0.78 | GAA (0.52) | ABCC9ABCC8KCNJ11KCNJ8NAMPT | |
| SCHEMBL436337 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TDP1LMNAKDM4ECYP2C9 | |
| SCHEMBL1576454 | 0.76 | ALDH1A1 (0.66) | ALDH1A1TDP1LMNAKDM4ECYP2C9 | |
| SCHEMBL8796811 | 0.75 | SLC40A1 (0.40) | ABCC9ABCC8KCNJ11KCNJ8NAMPT | |
| SCHEMBL6272514 | 0.73 | ALDH1A1 (0.40) | ABCC9ABCC8KCNJ11KCNJ8NAMPT | |
| SCHEMBL8017713 | 0.71 | KMT2A (0.62) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL4029409 | 0.71 | ABCC9 (0.48) | ABCC9ABCC8KCNJ11KCNJ8NAMPT | |
| SCHEMBL5757219 | 0.71 | LOXL2 (0.51) | ABCC9ABCC8KCNJ11KCNJ8NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |