Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14420060 | 0.92 | PTGS1 (0.50) | PTGS1PGRPDE4ACYP4F2CYP4A11 | |
| SCHEMBL14420108 | 0.84 | PPARA (0.40) | PTGS1PPARAPPARGCYP4F2CYP4A11 | |
| SCHEMBL25812372 | 0.82 | PTGS1 (0.44) | PTGS1PPARAPPARGCYP4F2CYP4A11 | |
| SCHEMBL27937246 | 0.81 | PPARA (0.44) | PPARAPPARGCYP4F2CYP4A11LPL | |
| SCHEMBL14420084 | 0.80 | TSHR (0.43) | PPARAPPARGLPLLIPG | |
| SCHEMBL19542673 | 0.77 | LPL (0.49) | PPARAPPARGLPLLIPGCYSLTR2 | |
| SCHEMBL14420102 | 0.75 | PTGS1 (0.39) | PTGS1CYP4F2CYP4A11TLR7PTGS2 | |
| SCHEMBL14420217 | 0.75 | PTGS2 (0.43) | PTGS1PGRPDE4APTGS2CYP2D6 | |
| SCHEMBL290381 | 0.74 | PPARA (0.51) | PTGS1PPARAPPARGLPLLIPG | |
| SCHEMBL18241996 | 0.72 | LPL (0.44) | PPARAPPARGLPLLIPGCYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | TLR7, CCR8, TLR8 | PTGS1 1192/4885PGR 3457/4885PDE4A 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.