Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14420102 | 0.92 | PTGS1 (0.39) | CYP4F2CYP4A11TLR7PTGS1PTGS2 | |
| SCHEMBL14420087 | 0.87 | PTGS2 (0.45) | PTGS1PTGS2 | |
| SCHEMBL25812372 | 0.85 | PTGS1 (0.44) | PPARAPPARGCYP4F2CYP4A11TLR7 | |
| SCHEMBL14420064 | 0.84 | PTGS1 (0.48) | PPARAPPARGCYP4F2CYP4A11TLR7 | |
| SCHEMBL14420107 | 0.79 | PPARA (0.46) | PPARAPPARGCYP4F2CYP4A11XIAP | |
| SCHEMBL19542673 | 0.78 | LPL (0.49) | PPARAPPARGLPLLIPGCYSLTR2 | |
| SCHEMBL27937246 | 0.77 | PPARA (0.44) | PPARAPPARGCYP4F2CYP4A11XIAP | |
| SCHEMBL14420060 | 0.75 | PTGS1 (0.50) | CYP4F2CYP4A11TLR7PTGS1PTGS2 | |
| SCHEMBL290381 | 0.75 | PPARA (0.51) | PPARAPPARGPTGS1PTGS2LPL | |
| SCHEMBL18025553 | 0.74 | TNKS2 (0.45) | CYP4F2CYP4A11CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | TLR7, CCR8, TLR8 | PPARA 2948/4885PPARG 2374/4885CYP4F2 1714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.