Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLI1 | P08151 | 1/20 | 0.34 |
| ▸ | GLI2 | P10070 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14420108 | 0.92 | PPARA (0.40) | PTGS1PTGS2TLR7CYP4F2CYP4A11 | |
| SCHEMBL14420087 | 0.89 | PTGS2 (0.45) | PTGS1PTGS2ALDH1A1MEN1KMT2A | |
| SCHEMBL14420060 | 0.83 | PTGS1 (0.50) | PTGS1PTGS2ALOX5TLR7CYP4F2 | |
| SCHEMBL2060445 | 0.78 | PTGS2 (0.54) | PTGS1PTGS2ALDH1A1ALOX5 | |
| SCHEMBL14420100 | 0.77 | SLC7A5 (0.43) | ALDH1A1ALOX5CYP4F2CYP4A11 | |
| SCHEMBL25812372 | 0.77 | PTGS1 (0.44) | PTGS1PTGS2ALDH1A1TLR7CYP4F2 | |
| SCHEMBL14420064 | 0.75 | PTGS1 (0.48) | PTGS1PTGS2TLR7CYP4F2CYP4A11 | |
| SCHEMBL14420075 | 0.75 | TSHR (0.47) | PTGS1PTGS2ALDH1A1ALOX5KMT2A | |
| SCHEMBL6696949 | 0.73 | ALDH1A1 (0.59) | ALDH1A1ALOX5CYP4F2CYP4A11 | |
| SCHEMBL17083283 | 0.71 | LOXL2 (0.45) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225303-A1 | 8-Oxoadenine Compound | TLR7, CCR8, TLR8 | PTGS1 1192/4885PTGS2 1288/4885ALDH1A1 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.