Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 6/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12121744 | 0.84 | DRD2 (0.39) | OPRM1CCR1DRD2DRD3DRD4 | |
| SCHEMBL12121691 | 0.84 | CCR1 (0.41) | OPRM1OPRL1CCR1DRD2DRD3 | |
| SCHEMBL10288264 | 0.83 | CCR3 (0.38) | CCR1DRD2DRD3 | |
| SCHEMBL13824277 | 0.82 | CCR1 (0.40) | OPRM1OPRL1CCR1DRD2DRD3 | |
| SCHEMBL14420162 | 0.82 | CCR1 (0.54) | OPRM1OPRL1CCR1DRD2DRD3 | |
| SCHEMBL13824278 | 0.82 | CCR1 (0.38) | OPRM1OPRL1CCR1DRD2ADRA1A | |
| SCHEMBL13824486 | 0.82 | CCR1 (0.39) | OPRM1OPRL1CCR1DRD2ADRA1A | |
| SCHEMBL12121740 | 0.80 | CCR1 (0.37) | OPRM1OPRL1CCR1DRD2ADRA1A | |
| SCHEMBL13824271 | 0.79 | CCR1 (0.38) | OPRM1CCR1DRD2DRD3DRD4 | |
| SCHEMBL14579853 | 0.78 | CCR1 (0.37) | OPRM1OPRL1CCR1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271176-B2 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-09-18 | — | — | US | disclosed |