Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 8/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12121691 | 0.88 | CCR1 (0.41) | CCR1DRD2OPRM1DRD4SLC6A4 | |
| SCHEMBL13824277 | 0.87 | CCR1 (0.40) | CCR1DRD2OPRM1ADRA2ADRD4 | |
| SCHEMBL12121744 | 0.85 | DRD2 (0.39) | CCR1DRD2OPRM1ADRA2ADRD4 | |
| SCHEMBL13824486 | 0.85 | CCR1 (0.39) | CCR1DRD2OPRM1OPRL1ADRA1A | |
| SCHEMBL13824278 | 0.83 | CCR1 (0.38) | CCR1DRD2OPRM1OPRL1ADRA1A | |
| SCHEMBL13824271 | 0.83 | CCR1 (0.38) | CCR1DRD2OPRM1ADRA2ADRD4 | |
| SCHEMBL652678 | 0.83 | CCR1 (0.64) | CCR1DRD2OPRM1ADRA2ADRD4 | |
| SCHEMBL12121740 | 0.82 | CCR1 (0.37) | CCR1DRD2OPRM1OPRL1ADRA1A | |
| SCHEMBL14579853 | 0.82 | CCR1 (0.37) | CCR1DRD2OPRM1ADRA2ADRD4 | |
| SCHEMBL14420129 | 0.82 | OPRM1 (0.39) | CCR1DRD2OPRM1DRD4OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271176-B2 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-09-18 | — | — | US | disclosed |