Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 7/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288264 | 0.86 | CCR3 (0.38) | CCR1ALDH1A1DRD2SMN1; SMN2 | |
| SCHEMBL13824277 | 0.84 | CCR1 (0.40) | CCR1DRD2OPRM1OPRL1ADRA1A | |
| SCHEMBL12121691 | 0.84 | CCR1 (0.41) | CCR1DRD2OPRM1OPRL1ADRA1A | |
| SCHEMBL12121744 | 0.83 | DRD2 (0.39) | CCR1DRD2OPRM1ADRA1A | |
| SCHEMBL14420162 | 0.82 | CCR1 (0.54) | CCR1DRD2SMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL13824486 | 0.81 | CCR1 (0.39) | CCR1DRD2OPRM1OPRL1ADRA1A | |
| SCHEMBL14579853 | 0.80 | CCR1 (0.37) | CCR1ALDH1A1DRD2OPRM1OPRL1 | |
| SCHEMBL14420129 | 0.80 | OPRM1 (0.39) | CCR1DRD2OPRM1OPRL1ADRA1A | |
| SCHEMBL13824278 | 0.80 | CCR1 (0.38) | CCR1DRD2OPRM1OPRL1ADRA1A | |
| SCHEMBL13824271 | 0.79 | CCR1 (0.38) | CCR1DRD2OPRM1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058287-B2 | Chemokine receptor antagonists and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-11-15 | — | — | US | disclosed |