SCHEMBL14423927

SCHEMBL14423927

OCc1cc2cnncc2cc1CO

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.44
PDE4B Q07343 1/20 0.44
PDE4C Q08493 1/20 0.44
PDE4D Q08499 1/20 0.44
ALDH1A1 P00352 3/20 0.39
GRIA1 P42261 1/20 0.36
GRIA2 P42262 1/20 0.36
GRIA3 P42263 1/20 0.36
GRIA4 P48058 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
HASPIN Q8TF76 1/20 0.34
KDM4E B2RXH2 2/20 0.32
PDXK O00764 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CBFB Q13951 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11321414 0.76 KDM4E (0.36) ALDH1A1GRIA1GRIA2GRIA3GRIA4
SCHEMBL672601 0.71 GRIA1 (0.48) PDE4APDE4BPDE4CPDE4DGRIA1
SCHEMBL22045619 0.71 ALDH1A1 (0.53) ALDH1A1HPGD
SCHEMBL14424504 0.70 CA2 (0.44) ALDH1A1HSD17B10
SCHEMBL29583446 0.69 PDE4A (0.46) PDE4APDE4BPDE4CPDE4DALDH1A1
SCHEMBL430273 0.69 PDE4A (0.46) PDE4APDE4BPDE4CPDE4DALDH1A1
SCHEMBL13156493 0.68 ALDH1A1 (0.50) ALDH1A1
SCHEMBL9666642 0.67 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL20687203 0.67 PDE4A (0.50) PDE4APDE4BPDE4CPDE4DGRIA1
SCHEMBL14904009 0.66 MAP4K4 (0.42) PDE4APDE4BPDE4CPDE4DALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070224554-A1 Photothermographic material FUJIFILM CORPORATION (JP) 2007-09-27 US disclosed
US-7229753-B2 Photothermographic material and method for forming images FUJIFILM CORPORATION (JP) 2007-06-12 US disclosed
US-7229753-B2 Photothermographic material and method for forming images FUJIFILM CORPORATION (JP) 2007-06-12 US disclosed
US-7223531-B2 Photothermographic material FUJIFILM CORPORATION (JP) 2007-05-29 US disclosed
US-20070003884-A1 Photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 2007-01-04 US disclosed