Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542224 | 0.81 | MAPT (0.48) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL5534383 | 0.78 | ALDH1A1 (0.45) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL12432958 | 0.78 | APP (0.44) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL7199847 | 0.78 | CA12 (0.56) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL1825941 | 0.78 | ALDH5A1 (0.43) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL22641649 | 0.76 | MAPT (0.41) | CYP2A6ALDH1A1ALDH1A3ALDH3A1TYR | |
| SCHEMBL15630935 | 0.76 | ALDH1A1 (0.47) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL21232552 | 0.76 | MAPT (0.40) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL1823957 | 0.76 | ALDH1A1 (0.38) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL7554959 | 0.76 | CYP2A6 (0.50) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7255853-B2 | Photoprotective cosmetic compositions containing aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile and novel aromatic amide, sulphonamide or carbamate derivatives of acrylonitrile | L'OREAL (FR) | 2007-08-14 | — | — | US | disclosed |