Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172276 | 0.84 | MAPT (0.45) | MAPTALDH1A1LMNAADRA2AADRA2B | |
| SCHEMBL5534383 | 0.83 | ALDH1A1 (0.45) | MAPTALDH1A1ALDH1A3ALDH3A1LMNA | |
| SCHEMBL12387901 | 0.81 | MAPT (0.47) | MAPTLMNAADRA2AADRA2BADRA2C | |
| SCHEMBL14423965 | 0.81 | CYP2A6 (0.44) | ALDH1A1ALDH1A3ALDH3A1CYP2A6TYR | |
| SCHEMBL8533249 | 0.81 | MAPT (0.47) | MAPTLMNAADRA2AADRA2BADRA2C | |
| SCHEMBL526383 | 0.80 | MAPT (0.58) | MAPTALDH1A1LMNAADRA2AADRA2B | |
| SCHEMBL9391329 | 0.79 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAADRA2AADRA2B | |
| Dimethylamine SCHEMBL5736373 | 0.79 | ALDH1A1 (0.42) | MAPTALDH1A1ALDH1A3ALDH3A1LMNA | |
| SCHEMBL5493605 | 0.79 | LMNA (0.43) | MAPTALDH1A1ALDH1A3ALDH3A1LMNA | |
| SCHEMBL13024625 | 0.78 | MAPT (0.42) | MAPTALDH1A1LMNAADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| JP-56029586-A | — | — | None | — | — | JP | disclosed |
| CN-118930497-A | Conjugate of c-di-GMP G-quadruplex inducer and NO donor and application thereof in antibacterial biomembrane | 暨南大学 | 2024-11-12 | — | — | CN | disclosed |
| CN-118894809-A | Isoliminox derivative and preparation method and application thereof | 深圳市新产业生物医学工程股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| US-20230050846-A1 | TREATMENT OF HEPATIC AND CARDIOVASCULAR DISORDERS | UNIVERSITÉ PAUL SABATIER TOULOUSE III (FR) | 2023-02-16 | — | — | US | disclosed |
| WO-2021123300-A1 | TREATMENT OF HEPATIC AND CARDIOVASCULAR DISORDERS | LIFESEARCH (FR) | 2021-06-24 | — | — | WO | disclosed |
| EP-2917203-B1 | METHOD FOR IDENTIFYING MYC INHIBITORS | DANA FARBER CANCER INST INC (US) | 2019-04-03 | — | — | EP | disclosed |
| CN-103571456-A | Fluorescence probe for detecting nitrosyl peroxide by utilizing amido bond rupture and application of fluorescence probe | DALIAN CHEMICAL PHYSICS INST | 2014-02-12 | — | — | CN | disclosed |
| WO-2013148892-A1 | BENZYLIDENE DERIVATIVE CHROMOPHORES FOR PHOTOREFRACTIVE COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2013-10-03 | — | — | WO | disclosed |
| US-20130170016-A1 | PHOTOREFRACTIVE DEVICE CONTAINING A CHROMOPHORE-DOPED POLYMER LAYER AND ITS MANUFACTURING METHOD | NITTO DENKO CORPORATION (JP) | 2013-07-04 | — | — | US | disclosed |
| US-5443758-A | A ketone cis- or trans-gonanes; nonlinear optical response | HATACHI CHEMICAL COMPANY, LTD. (JP) | 1995-08-22 | — | — | US | disclosed |
| EP-0290610-B1 | METHOD FOR INSPECTING BODILY FLUIDS | DAINIPPON PRINTING CO LTD (JP) | 1994-08-17 | — | — | EP | disclosed |
| EP-0605394-A1 | Device for testing body fluids | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5262090-A | Electrooptical switches | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| US-5208341-A | Pressure sensitive copying; thermoreactive or electrochromic recording materials | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | disclosed |
| US-5178831-A | Colorimetric analysis for medical diagnosis | DAI NIPPON INSATSU KAB USHIKI KAISHA | 1993-01-12 | — | — | US | disclosed |
| EP-0480276-A2 | Carbonylaminostyrene derivatives as recording material | BAYER AG (DE) | 1992-04-15 | — | — | EP | disclosed |
| EP-0465155-A2 | Non-linear optical material containing steroidal ketone compound | Hitachi Chemical Co., Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |
| EP-0290610-A1 | METHOD FOR INSPECTING BODILY FLUIDS | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1988-11-17 | — | — | EP | disclosed |
| JP-S5629586-A | 2,6-DI-TERT-BUTYL-4- 4- DIETHYLAMINO STYRYL THIOPYRYLIUM SALT AND ITS PREPARATION | FUJI PHOTO FILM CO LTD | 1981-03-24 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230050846-A1 | TREATMENT OF HEPATIC AND CARDIOVASCULAR DISORDERS | FABP1, FABP3, PCSK9 | MAPT 3463/4885ALDH1A1 974/4885ALDH1A3 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.