Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 11/20 | 0.56 |
| ▸ | RXRB | P28702 | 11/20 | 0.56 |
| ▸ | RXRG | P48443 | 9/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL969589 | 0.84 | HPGD (0.55) | ABCC4LMNAGAATSHRPTGS1 | |
| Hydrochloric Acid SCHEMBL2530255 | 0.82 | HPGD (0.53) | LMNAGAATSHRPTGS1CA2 | |
| SCHEMBL68027 | 0.82 | LMNA (0.86) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL18427891 | 0.82 | LMNA (0.86) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL10228775 | 0.80 | ABCC4 (0.69) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL12126599 | 0.80 | LMNA (0.75) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL12087753 | 0.79 | ABCC4 (0.67) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL18427881 | 0.79 | ABCC4 (0.80) | ABCC4LMNAGAATSHRPTGS1 | |
| SCHEMBL6295539 | 0.76 | ABCC4 (0.69) | ABCC4LMNAGAATSHRPTGS1 | |
| Felbinac SCHEMBL7107700 | 0.76 | LMNA (0.91) | ABCC4LMNAGAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273861-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2007-09-25 | — | — | US | disclosed |