SCHEMBL969589

SCHEMBL969589

Cc1ccc(CC(=O)O)cc1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.55
HSD17B10 Q99714 5/20 0.55
GAA P10253 5/20 0.55
KDM4E B2RXH2 4/20 0.55
TSHR P16473 4/20 0.55
MAPT P10636 3/20 0.55
LMNA P02545 3/20 0.55
NFKB1 P19838 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
RGS12 O14924 1/20 0.55
POLB P06746 1/20 0.55
APEX1 P27695 1/20 0.55
THPO P40225 1/20 0.55
BLM P54132 1/20 0.55
GNAI1 P63096 1/20 0.55
PMP22 Q01453 1/20 0.55
HIF1A Q16665 1/20 0.55
SLC22A12 Q96S37 1/20 0.53
ALDH1A1 P00352 5/20 0.52
CA2 P00918 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2530255 0.98 HPGD (0.53) HPGDHSD17B10GAAKDM4ETSHR
SCHEMBL18461814 0.84 LMNA (0.47) GAAKDM4ELMNAPOLBALDH1A1
SCHEMBL14425199 0.84 ABCC4 (0.60) GAATSHRLMNACA2PTGS1
SCHEMBL1362192 0.83 HPGD (0.68) HPGDHSD17B10GAAKDM4ETSHR
SCHEMBL4066457 0.83 HPGD (0.68) HPGDHSD17B10GAAKDM4ETSHR
SCHEMBL30523685 0.83 HPGD (0.68) HPGDHSD17B10GAAKDM4ETSHR
SCHEMBL10534540 0.83 ALDH1A1 (0.50) GAALMNAALDH1A1MEN1KMT2A
SCHEMBL2283410 0.83 RXRA (0.53) HPGDHSD17B10GAAKDM4ETSHR
SCHEMBL12900623 0.83 LMNA (0.46) GAALMNAPOLBALDH1A1MEN1
SCHEMBL1259978 0.83 LMNA (0.46) GAAKDM4EMAPTLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116287276-A Liver cancer biological marker and application thereof 浙江大学医学院附属第一医院 2023-06-23 CN claimed
CN-119431382-A Tetrahydrothebaine derivative and preparation method and application thereof 中国科学院上海药物研究所 2025-02-14 CN disclosed
CN-115023413-B Rearrangement of dimethylphenylacrylate using zeolite 帝斯曼知识产权资产管理有限公司 2024-11-15 CN disclosed
WO-2023235929-A1 FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USES THEREOF NOXOPHARM LIMITED (AU) 2023-12-14 WO disclosed
WO-2023235929-A1 FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USES THEREOF NOXOPHARM LIMITED (AU) 2023-12-14 WO disclosed
CN-117024371-A Compound with function of reversing PD-1 drug resistance and application thereof 中国人民解放军海军军医大学 2023-11-10 CN disclosed
US-20230348779-A1 FLUORESCENT COMPOUND AND FLUORESCENTLY LABELED BIOLOGICAL SUBSTANCE USING THE SAME FUJIFILM CORPORATION (JP) 2023-11-02 US disclosed
EP-4100385-A1 REARRANGEMENT OF DIMETHYLPHENYLACYLATES USING ZEOLITES DSM IP Assets B.V. (NL) 2022-12-14 EP disclosed
CN-115023413-A Rearrangement of dimethylphenyl acrylate using zeolite 帝斯曼知识产权资产管理有限公司 2022-09-06 CN disclosed
CN-109053630-B Benzothiazole derivative and application thereof 中国人民解放军第二军医大学 2022-04-01 CN disclosed
EP-0817772-A1 PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS PFIZER INC. (US) 1998-01-14 EP disclosed
WO-1996030339-A1 PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS PFIZER INC. (US) 1996-10-03 WO disclosed
US-RE33906-E Cyclic carboxamide derivatives and their use as analgesics DR.LO.ZAMBELETTI S.P.A. (IT) 1992-04-28 US disclosed
US-4952721-A AIR OXIDATION WITH HEAVY METAL CATALYSTS AMOCO CORPORATION (US) 1990-08-28 US disclosed
EP-0232612-B1 AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICALS Dr. Lo. Zambeletti S.p.A. (IT) 1990-04-04 EP disclosed
US-4801585-A Cyclic carboxamide derivatives and their use as analgesics DR.LO.ZAMBELETTI S.P.A. (IT) 1989-01-31 US disclosed
EP-0232612-A1 Azacyclic compounds, processes for their preparation, and their use as pharmaceuticals Dr. Lo. Zambeletti S.p.A. (IT) 1987-08-19 EP disclosed
US-4390723-A BIS(8-QUINOLINOLATE) COPPER COMPLEX CATALYST IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1983-06-28 US disclosed
US-4203896-A WITH MERCURIC ACETATE AND ACETIC ACID, ACIDIC HYDROLYSIS OF N-PROPENYL GROUP ELI LILLY AND COMPANY (US) 1980-05-20 US disclosed
US-4144232-A Substituted azetidin-2-one antibiotics ELI LILLY AND COMPANY (US) 1979-03-13 US disclosed