Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA2 | O43464 | 8/20 | 0.43 |
| ▸ | HTRA1 | Q92743 | 8/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14426888 | 0.95 | HTRA2 (0.41) | HTRA2HTRA1FOLH1ALB | |
| SCHEMBL9906219 | 0.93 | FOLH1 (0.49) | HTRA2HTRA1FOLH1ALB | |
| SCHEMBL13780483 | 0.91 | FOLH1 (0.44) | HTRA2HTRA1FOLH1 | |
| SCHEMBL9906147 | 0.88 | FOLH1 (0.46) | HTRA2HTRA1FOLH1ALB | |
| SCHEMBL18699632 | 0.85 | HTRA2 (0.36) | HTRA2HTRA1FOLH1ALB | |
| SCHEMBL9906265 | 0.84 | FOLH1 (0.51) | HTRA2HTRA1FOLH1ALB | |
| SCHEMBL14402386 | 0.84 | FOLH1 (0.50) | HTRA2HTRA1FOLH1ALB | |
| SCHEMBL9906146 | 0.82 | CA9 (0.46) | — | |
| SCHEMBL1688103 | 0.82 | FOLH1 (0.55) | HTRA2HTRA1FOLH1ALB | |
| SCHEMBL14427154 | 0.81 | FOLH1 (0.45) | HTRA2HTRA1FOLH1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7255999-B2 | Detection of preferential polypetide in sample; otain sample containing preferential polyeptide, electrophorese, incubate with probe, detect signal from probe and recover polypeptide | MONOGRAM BIOSCIENCES, INC. (US) | 2007-08-14 | — | — | US | disclosed |