Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | HTRA2 | O43464 | 7/20 | 0.40 |
| ▸ | HTRA1 | Q92743 | 7/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14426888 | 0.96 | HTRA2 (0.41) | FOLH1HTRA2HTRA1 | |
| SCHEMBL9906265 | 0.93 | FOLH1 (0.51) | FOLH1BTKHTRA2HTRA1HTR3A | |
| SCHEMBL14426890 | 0.91 | HTRA2 (0.43) | FOLH1HTRA2HTRA1 | |
| SCHEMBL9906147 | 0.89 | FOLH1 (0.46) | FOLH1HTRA2HTRA1 | |
| SCHEMBL9906219 | 0.84 | FOLH1 (0.49) | FOLH1HTRA2HTRA1 | |
| SCHEMBL14402386 | 0.83 | FOLH1 (0.50) | FOLH1HTRA2HTRA1 | |
| SCHEMBL14427133 | 0.82 | FOLH1 (0.46) | FOLH1BTKHTRA2HTRA1HTR3A | |
| SCHEMBL14427154 | 0.80 | FOLH1 (0.45) | FOLH1HTRA2HTRA1 | |
| SCHEMBL9906229 | 0.80 | FOLH1 (0.51) | FOLH1BTKHTRA2HTRA1 | |
| SCHEMBL14427794 | 0.80 | FOLH1 (0.44) | FOLH1HTRA2HTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090173631-A1 | Single Cell Analysis of Membrane Molecules | ACLARA BIOSCIENCES, INC. | 2009-07-09 | — | — | US | disclosed |