Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.39 |
| ▸ | HTRA2 | O43464 | 3/20 | 0.37 |
| ▸ | HTRA1 | Q92743 | 3/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14526054 | 0.95 | FOLH1 (0.41) | FOLH1ALBESR1HAVCR2HTRA2 | |
| SCHEMBL17010839 | 0.94 | FOLH1 (0.45) | FOLH1ALBESR1HTRA2HTRA1 | |
| SCHEMBL9906229 | 0.92 | FOLH1 (0.51) | FOLH1ALBBTKESR1HTRA2 | |
| SCHEMBL9906326 | 0.91 | FOLH1 (0.56) | FOLH1ALBBTKESR1HAVCR2 | |
| SCHEMBL14427154 | 0.90 | FOLH1 (0.45) | FOLH1ALBESR1HTRA2HTRA1 | |
| SCHEMBL9906192 | 0.88 | ALB (0.49) | FOLH1ALBESR1HTRA2HTRA1 | |
| SCHEMBL9906327 | 0.88 | FOLH1 (0.52) | FOLH1ALBESR1HAVCR2 | |
| SCHEMBL9906226 | 0.87 | ALB (0.49) | FOLH1ALBESR1HTRA2HTRA1 | |
| SCHEMBL1688099 | 0.86 | FOLH1 (0.51) | FOLH1ALBESR1HAVCR2 | |
| SCHEMBL9906261 | 0.85 | ALB (0.52) | FOLH1ALBHTRA2HTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7255999-B2 | Detection of preferential polypetide in sample; otain sample containing preferential polyeptide, electrophorese, incubate with probe, detect signal from probe and recover polypeptide | MONOGRAM BIOSCIENCES, INC. (US) | 2007-08-14 | — | — | US | disclosed |